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Name:Talabostat
Catalog No.:B0017
Structure:
Chemical Properties Cas No.:150080-09-4 Purity Limit: Synonyms: Molecular Weight:214.07 Formula:C9H19BN2O3 Storage: Solubility:
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Quality Control & MSDS
Description Talabostat mesylate is the orally bioavailable mesylate salt of an amino boronic dipeptide with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines
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