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Name:Ixazomib
Catalog No.:B0009
Structure:
Chemical Properties Cas No.:1201902-80-8 Purity Limit: Synonyms: Molecular Weight:516.09 Formula:C20H23BCl2N2O9 Storage: Solubility:
Shipping Condition
Quality Control & MSDS
Description ixazomib, also known as MLN-9708, is an orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. Ixazomib inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome, which results in an accumulation of unwanted or misfolded proteins; disruption of various cell signaling pathways may follow, resulting in the induction of apoptosis. Compared to first generation PIs, second generation PIs may have an improved pharmacokinetic profile with increased potency and less toxicity. Proteasomes are large protease complexes that degrade unneeded or damaged proteins that have been ubiquinated
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