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Name:XJ735
Catalog No.:A0035
Structure:
Chemical Properties Cas No.:153381-95-4 Purity Limit: Synonyms:Cyclo(-Ala-Arg-Gly-Asp-3-aminomethylbenzoyl) Trifluoroacetate salt Molecular Weight:532.56 Formula:C23H32N8O7 Storage: Solubility:
Shipping Condition
Quality Control & MSDS
Description This small molecule RGD peptidomimetic αvβ3 integrin antagonist contains both anionic and cationic binding sites that straddle the RGD binding domain of the αvβ3 integrin. The IC for XJ 735 αvβ3-mediated inhibition of human and porcine cell adhesion, and vascular smooth muscle cell migration, ranged from 0.6 to 4.4 μM. In contrast, IC for porcine or human αIIb/β3, α4β1, αvβ5, and α5β1 inhibition exceeded 100 μM
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