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Name:Astressin
Catalog No.:A0026
Chemical Properties Cas No.:170809-51-5 Purity Limit: Synonyms:H-D-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-cyclo(-Glu-Ala-His-Lys)-Asn-Arg-Lys-Leu-Nle-Glu-Ile-Ile-NH Trifluoroacetate salt Molecular Weight:3563.16 Formula:C161H269N49O42 Storage: Solubility:
Shipping Condition
Quality Control & MSDS
Description The Glu3 to Lys33 lactam bridge constrains astressin in an α-helical conformation which seems to be responsible for its especially high CRF antagonist activity. Astressin is 100 times more potent than α-helical CRF (9-41) (H-2040) at inhibiting ACTH secretion in vitro, and more than 10 times more potent in vivo than any other CRF antagonist reported to date
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